Table 2

Characteristics of the 16 common differentially expressed mRNAs

SymbolDescriptionEnsemblRegulationPrimary function
CA1Carbonic anhydrase 1ENSG00000133742UpCatalyzing the reversible hydration of carbon dioxide
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4ENSG00000110080UpParticipating in protein glycosylation
PAQR5Progestin and adipoQ receptor family member 5ENSG00000137819UpPlasma membrane progesterone (P4) receptor coupled to G proteins
IL1RL1Interleukin 1 receptor like 1ENSG00000115602UpThe interleukin 1 receptor family involved in the function of helper T cells
F2RL1F2R like trypsin receptor 1ENSG00000164251UpThe G-protein coupled receptor 1 family followed by PLC, MAPK, IKK/NF-κB, and Rho signaling
KCNN2Potassium calcium-activated channel subfamily N member 2ENSG00000080709UpRegulating neuronal excitability by contributing to the slow component of synaptic AHP
SLC36A4Solute carrier family 36 member 4ENSG00000180773UpA sodium-independent electroneutral transporter for amino acids
PIM3Pim-3 proto-oncogene, serine/threonine kinasepENSG00000198335UpA proto-oncogene with serine/threonine kinase activity, regulating cell apoptosis
SORBS2Sorbin and SH3 domain containing 2ENSG00000154556UpThe member of the Abelson family of non-receptor protein–tyrosine kinases
CRB1Crumbs cell polarity complex component 1ENSG00000134376UpParticipating in photoreceptor morphogenesis in the retina
CHUKComponent of inhibitor of nuclear factor kappa B kinase complexENSG00000213341UpA component of a cytokine-activated protein complex as an inhibitor of NF-κB
ABCG5ATP-binding cassette subfamily G member 5ENSG00000138075DownMediating Mg (2+)-dependent and ATP-dependent sterol transport across the cell membrane
C1orf115Chromosome one open reading frame 115ENSG00000162817DownBeing associated with spastic paraplegia and autosomal recessive
EGFL6EGF like domain multiple 6ENSG00000198759DownA member of EGF repeat superfamily involved in the cell cycle, proliferation, and developmental processes
RND2Rho family GTPase 2ENSG00000108830DownA member of the Rho GTPase family, regulating neuronal morphology and endosomal trafficking
PGPEP1Pyroglutamyl-peptidase IENSG00000130517DownA member of the peptidase C15 family
  • AHP, afterhyperpolarization; CHUK, conserved helix–loop–helix ubiquitous kinase; EGF, epidermal growth factor; IKK, IκB kinase; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor kappa B; PLC, phospholipase C; SH3, src homology.