Characteristics of the studies included in this meta-analysis of VEGFA rs3025039 polymorphism
Study | Population | Area | Race | Sample size | Genotype in cases | Genotype in controls | Minor allele frequency in controls (%) | HWE p value in controls | Type of study | Genotyping method | Quality score | |||||
Cases | Controls | CC | CT | TT | CC | CT | TT | |||||||||
Lee et al10 | Chinese | Southern | Asian | 45 | 160 | 37 | 8 | 0 | 91 | 62 | 7 | 23.8 | >0.05 | Hospital-based | TaqMan | 6 |
Liu et al11 | Chinese | Northwestern | Asian | 311 | 1205 | 220 | 86 | 5 | 620 | 355 | 50 | 22.2 | 0.929 | Hospital-based | MassARRAY | 6 |
Liu et al12 | Chinese | Southern | Asian | 490* | 1456* | 332 | 142 | 16 | 1002 | 411 | 43 | 17 | 0.874 | Hospital-based | MassARRAY | 9 |
*The number of cases and controls was calculated from the publication.
HWE, Hardy-Weinberg equilibrium; VEGFA, vascular endothelial growth factor A.