Modified COG Evans staging system (CCCG-HB-2016)6
Stage | Definition |
Stage Ia | Complete resection, PFH. |
Stage Ib | Complete resection, non-PFH. |
Stage II | Incomplete resection with microscopic residue. |
Stage III | Incomplete resection with macroscopic residue. Incomplete resection with positive lymph nodes. Tumor rupture or intraperitoneal bleeding. |
Stage IV | Distant metastasis at diagnosis, whether primary lesion resection or not. |
CCCG-HB-2016, Chinese Anti-Cancer Association Pediatric Committee Hepatoblastoma consensus 2016; COG, Children’s Oncology Group; HB, hepatoblastoma; PFH, pure fetal histology.