Table 1

Modified COG Evans staging system (CCCG-HB-2016)6

StageDefinition
Stage IaComplete resection, PFH.
Stage IbComplete resection, non-PFH.
Stage IIIncomplete resection with microscopic residue.
Stage IIIIncomplete resection with macroscopic residue.
Incomplete resection with positive lymph nodes.
Tumor rupture or intraperitoneal bleeding.
Stage IVDistant metastasis at diagnosis, whether primary lesion resection or not.
  • CCCG-HB-2016, Chinese Anti-Cancer Association Pediatric Committee Hepatoblastoma consensus 2016; COG, Children’s Oncology Group; HB, hepatoblastoma; PFH, pure fetal histology.