The Children’s Oncology Group standard chemotherapy regimens for Wilms tumor8
| Regimen name | Regimen description |
| Regimen EE-4A | Vincristine, dactinomycin ×18 weeks postnephrectomy |
| Regimen DD-4A | Vincristine, dactinomycin, doxorubicin ×24 weeks; baseline nephrectomy or biopsy with subsequent nephrectomy |
| Regimen I | Vincristine, doxorubicin, cyclophosphamide, etoposide ×24 weeks postnephrectomy |
| Regimen M | Vincristine, dactinomycin, doxorubicin, cyclophosphamide, and etoposide with subsequent radiation therapy |