RT Journal Article SR Electronic T1 Role of daily anal stimulation for intractable functional constipation in infants JF World Journal of Pediatric Surgery JO World Jnl Ped Surgery FD BMJ Publishing Group Ltd SP e000135 DO 10.1136/wjps-2020-000135 VO 3 IS 2 A1 Zhu, Tianqi A1 Sun, Xiaoyi A1 Zhu, Dan A1 You, Qian A1 Wan, Xiaoting A1 Meng, Xinyao A1 Feng, Jiexiong YR 2020 UL http://wjps.bmj.com/content/3/2/e000135.abstract AB Objective Functional constipation is one of the most common problems in pediatric gastroenterology. The aim of the present study was to evaluate the effectiveness of daily anal stimulation in infants with intractable functional constipation (IFC). Our evaluation was based on clinical improvement and on changes in manometric parameters through time.Methods Infants with IFC treated between January 2018 and December 2019 were included in this retrospective study. Treatment processing included daily anal stimulation for infants and psychological counseling for parents. All cases underwent a complete intervention program and were evaluated for improvement in symptoms and for changes in anorectal manometry within 1 year of follow-up.Results A total of 161 patients were included in this study. Positive response was achieved in all patients. Frequency of defecation, change in stool form and decrease in the defecatory pain were significantly relieved in all infants after intervention. On anorectal manometry, no significant difference was found in the peristaltic frequency of distal rectum before and after treatment. There was a significant increase in the mean amplitude of peristalsis and improvement in the rhythm after intervention. In the 1 year of follow-up, three patients had recurrence of constipation requiring colectomy.Conclusion In terms of the high clinical efficacy and limited side effects, daily anal stimulation may be included in the initial part of an intervention program for IFC in infants.